The Dr. Paul Janssen Research Center -
"A Perfect Solution for Pharmaceutical Discovery" (Belgium)
Bart Wens, Janssen Pharmaceutica
Ed Royzman, PE
Charles English, Strategic Science &
Dr. Paul Janssen Research Center, at Janssen Pharmaceutica Belgium,
is a 18,500-square meter (200,000 gross square foot) building reflecting
the research strategy of J&J's Pharmaceutical R&D objectives
in Belgium. The ultramodern facility has a functional focus on drug
discovery and is organized around the following principles:
- Keep disease area groups together to maximize communication
- Maximize sharing of lab resources for better efficiency
- Maximize communication between Pharmacology and Medicinal Chemistry
- Optimize access to the vivarium for groups with in-vivo activities
The key planning concepts to achieve this focus and promote interaction
between scientists are flexibility of laboratory spaces & systems
along with occupant comfort and safety. The "open modular"
lab unit concept facilitates communication between scientists, allows
for sharing not only the space itself, but also equipment and bench
space and makes the space more easily adaptable for future needs.
The design of the Center, with a focus on the naturally lighted
indoor atrium, the break areas, bridges, conference rooms, and other
meeting areas, are intended to contribute to opportunities for interaction
to achieve the magnification and expansion of ideas among the scientists.
The facility is a flagship building on the campus and as such is
designed to contribute to the "bottom line" by being a
sustainable, high performance, yet low-energy facility. By the fall
of 2005, sufficient data will have been collected over the course
of the first full year of operation in order to both track the performance
of the laboratory and to enable the Project Team to share ongoing
goals and results.
State-of-the art energy efficient engineering systems support the
flexible laboratory concept, provide redundancy where required for
safety and to maintain required environmental conditions. The Center
- Reducing the energy use and the volume of conditioned fresh
air by using radiant cooling (cold ceilings) in offices, conference
rooms, and office support area
- Using central variable flow supply and exhaust systems in the
- Using manifolded ductwork (at each floor level) to reduce total
exhaust and supply air volume by 35 percent compared to the connected
- Utilizing run-around coils for the heat recovery from exhaust
- Reducing water usage by utilizing a central recirculating cooling
system for rotary evaporators cooling in medicinal chemistry labs
- Utilizing central automated solvent distribution and solvent
waste collection system to improve lab safety and reduce the volume
of solvent stored in the lab
- Using photovoltaic panels in the atrium skylights synchronized
with the building power system to augment power usage and act
as a shading device
- Utilizing an air displacement system for the atrium heating
and air conditioning requirements
- Maximizing the use of daylight in the lab and in the building
to minimize the reliance on artificial light.
- Using infrared and motion detectors to control lights
Bart Wens served as a Project
Manager for Van Looy Group an architectural/engineering firm in
Antwerp, Belgium from 1989 to 1993 and than as a Project Director
for Janssen Pharmaceutica NV, division of J&J from 1993 until
the present time. Mr. Wens speaks four languages and leads projects
for J&J not only in Belgium, but also in France, Holland and
Switzerland. His latest project was the New Discovery Research Center
(Dr. Paul Janssen Research Center) for J&J Pharmaceutical Research
and Development in Beerse, Belgium for which he was the Project
Director. He received his MS in Architecture from Gent University,
Belgium and his MS in Business Administration from Vierick School
of Management, Belgium.
Eduard (Ed) Royzman,
PE, served in the position of HVAC group leader with an architectural
and engineering firm in Kiev, Ukraine, until 1979. He then immigrated
to the United States and served as a Principal of nationally recognized
architecture and engineering firms in Toledo, Ohio, and Washington,
DC. Mr. Royzman has developed an international reputation for projects
characterized by "practical innovation" in system solutions
that embrace all elements of building engineering and technology.
His experience has been gained working on a variety of projects
ranging from research and development facilities, pharmaceutical
facilities, food plants, and automotive plants to universities,
office buildings, hospitals and hotels. He has completed projects
across the US as well as in England, Belgium, Netherlands, Spain,
Israel, Mexico, Canada, Japan, Korea and Turkey. With a portfolio
including projects of significant size and scale from around the
world, Mr. Royzman has gained a perspective that allows him to address
the most complex technical challenges.
Recent projects include:
- New Discovery Research Center (Dr. Paul Janssen Research
Center) for J&J Pharmaceutical Research and Development in
Beerse, Belgium. Engineering services for the 18,500 square
meter (200,000 gross square foot) facility.
- National Institutes of Health. Replacement of HVAC
systems for 3.5 million square foot Clinical Center Complex at
the National Institutes of Health, Bethesda, MD.
- Sabanci University. New $250 million 3,000 students
Sabanci University in Istanbul, Turkey.
- Science and Education Park. 30 million square foot
Science and Education Park in Shanghai, China.
- University of Hawaii. 460-acre Research and Outreach
Center for University of Hawaii at Oahu, Hawaii.
- Honda of America. 450,000 square foot Research and
Development Center for prototype cars for Honda of America Manufacturing,
Inc., in Marysville, OH.
Mr. Royzman received his BS in Mechanical Engineering from Engineering
College, Kiev, Ukraine. Mr. Royzman is a registered engineer in
DC, FL, MD, OH, PA, VA, and WV.
Charles (Cory) English
has been a Principal with SST Planners for 11 years has distinguished
himself through his intimate knowledge of research and development
facilities. He has worked at all levels of the facility delivery
process, including programming, design, and management. The following
projects are representative of his extensive experience in laboratory
design and planning:
- New Discovery Research Center (Dr. Paul Janssen Research
Center) J&J Pharmaceutical Research and Development in Beerse,
Belgium. Programming and laboratory planning for the18,500
square meter (200,000 gross square foot) facility.
- University of Virginia. Programming, laboratory and
vivarium design for the new 14,000 sm (150,000 gross square foot)
Biomedical Engineering and Medical Sciences Building.
- Massachusetts Institute of Technology. Programming
of a 18,500 net square meter (200,000 net square foot) facility
housing the McGovern Institute for Brain Research, Center for
Learning and Memory, the Department of Brain and Cognitive Sciences,
and the Martinos Biomedical Imaging Center.
- University of Maryland Biotechnology Institute.
Programming and planning of a 13,000 square meter (140,000 gross
square foot) biomedical research facility for The Center for Advanced
Research in Biotechnology (CARB) at its Shady Grove, MD Campus.
- National Institutes of Health. Programming,
laboratory planning, and laboratory design of the new Dale and
Betty Bumpers Vaccine Research Center, a 7,800 square meter (84,000
gross square foot) facility that will initially be utilized principally
to develop a vaccine for AIDS.
- Centers for Disease Control. Programming and planning
of the Chamblee Laboratory Buildings 103 and 110 (a LEED™-Gold
Project) which support the National Center for Environmental Health
Mr. English holds a MS in Architecture from the Harvard Graduate
School of Design; 1976. He also received a BS in Architecture from
the University of Southern California in 1974, and a BS in Pre-Veterinary
Medicine from Pennsylvania State University in 1967.
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